Management tracks: Five Prime, Alder

Five Prime Therapeutics Inc. (NASDAQ:FPRX) hired David Smith as EVP and CFO, effective Nov. 26. He will replace Linda Rubinstein, who was interim CFO of the cancer company. Smith was COO of IntegenX Inc. until its acquisition this year by Thermo Fisher Scientific Inc. (NYSE:TMO).

Metabolic company Jnana Therapeutics Inc. (Boston, Mass.) named co-founder and President Joanne Kotz as CEO. She succeeds board member Amir Nashat, who was interim CEO. Jnana launched last December with a $50 million series A round from Polaris Partners, Avalon Ventures, Versant Ventures, AbbVie Ventures and Pfizer R&D Innovate...