ARTICLE | Preclinical News
Researchers suggest GPX4 inhibition to treat drug-resistant cancer
November 2, 2017 11:32 PM UTC
In a paper published in Nature, researchers at the University of California San Francisco and colleagues showed that persister cells from a range of cancers depend on glutathione peroxidase 4 (GPX4) for survival, suggesting that inhibiting GPX4 could help treat several drug-tolerant cancers.
Persister cancer cells survive targeted therapies through non-mutational mechanisms...
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