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ARTICLE | Preclinical News

Targeting a GPCR for alcohol addiction

June 27, 2018 7:55 PM UTC

Researchers at The Scripps Research Institute identified a GPCR in a brain region associated with drug and alcohol addiction as a new molecular target that could help treat alcohol abuse.

In a paper published in eNeuro, the scientists showed a tool compound developed by the Janssen Research & Development LLC unit of Johnson & Johnson (NYSE:JNJ) that activates G protein-coupled receptor 139 (GPR139) reduced alcohol intake in alcohol-dependent rats when delivered both systemically and via microinjection in the habenula...