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ARTICLE | Preclinical News

STING inhibitors could treat NASH

December 21, 2018 12:04 AM UTC

A paper in this week's edition of The Journal of Clinical Investigation expands the list of indications that could be treated by targeting the STING pathway, suggesting that inhibiting the cytosolic DNA sensor could help treat non-alcoholic steatohepatitis.

A team led by researchers from Second Military Medical University and Shanghai Jiao Tong University showed in the paper that a homozygous loss-of-function STING mutation attenuated progression of NASH in mice...