BioCentury
ARTICLE | Cover Story

Channel-tuning neuropathy

May 31, 2012 7:00 AM UTC

An international team has shown that a peptide inhibitor of methylglyoxal treated hypersensitivity to pain in diabetic mice.1 Although future studies could determine whether the mechanism plays a role in other types of neuropathic pain, the team is now seeking venture dollars to help spin out a new company based on the findings.

Painful diabetic neuropathy (PDN) is a subset of diabetic neuropathy that involves peripheral burning and tingling sensations and hypersensitivity to thermal or mechanical stimuli that are not ordinarily painful...