BioCentury
ARTICLE | Distillery Techniques

Techniques: Transgenic mutant cryptochrome circadian clock 2 (CRY2) knock-in mice as models of familial advanced sleep phase disorder

September 29, 2016 7:00 AM UTC

Transgenic mice expressing mutant human CRY2 could be used to screen therapies for familial advanced sleep phase disorder. Genetic sequencing of about 25 circadian genes in multiple families with a hi...