BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Guanosine 5'-diphosphate 3'-diphosphate (ppGpp); guanosine 5'-triphosphate 3'-diphosphate (pppGpp)

March 26, 2015 7:00 AM UTC

In vitro and insect studies suggest that D-enantiomeric anti-microbial peptides inhibiting ppGpp and pppGpp could help treat bacterial infections by eliminating biofilms. Chemical synthesis and in vit...