ARTICLE | Distillery Therapeutics
Therapeutics: Lactate dehydrogenase A (LDHA); TP53 induced glycolysis regulatory phosphatase (TIGAR)
July 30, 2015 7:00 AM UTC
Mouse and patient sample studies suggest inhibiting LDHA, which is required for glycolysis, could help treat p53-mutant pancreatic cancers. Levels of the glycolytic regulator TIGAR were lower in human...