BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Interferon regulatory factor 5 (IRF5); chemokine CXC motif ligand 1 (CXCL1; GRO; MGSA)

September 17, 2015 7:00 AM UTC

Mouse studies suggest inhibiting IRF5 could help treat inflammatory diseases. In a mouse model of antigen-induced arthritis, IRF5 knockout decreased knee swelling, synovial membrane thickening, synovi...