BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: NAD(P) dependent steroid dehydrogenase-like (NSDHL); K-Ras (KRAS)

October 15, 2015 7:00 AM UTC

Cell culture and mouse studies suggest inhibiting NSDHL could help treat mutant KRAS-driven cancer. In a transgenic mouse fibroblast cell line expressing an oncogenic mutation of human KRAS, NSDHL kno...