BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Drug-responsive transcription factor PDR1 (PDR1); mediator complex subunit 15 (MED15)

March 24, 2016 7:00 AM UTC

Cell culture, moth and mouse studies suggest inhibiting the microbial PDR1-MED15 interaction could help treat multidrug-resistant (MDR) fungal infections, which frequently involve gain-of-function mut...