BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Gap junction protein α 1, 43kDa (GJA1; CX43; connexin-43); protocadherin 7 (PCDH7)

June 2, 2016 7:00 AM UTC

Patient sample and mouse studies suggest inhibiting GJA1 or PCDH7 could help treat brain metastases of breast cancer, NSCLC and other solid tumor types. In 189 triple-negative breast cancer (TNBC) pat...