BioCentury
ARTICLE | Targets & Mechanisms

Promoting pain resolution

April 22, 2010 7:00 AM UTC

Harvard Medical Schoolresearchers have shown that resolvins could help treat inflammatory pain without the side effects associated with opioids and COX-2 inhibitors.1 The findings could open up a new indication for Resolvyx Pharmaceuticals Inc., which is developing resolvins to treat inflammatory indications.

Charles N. Serhan, professor of anesthesiology at the medical school, led a research group that discovered resolvins in 2000 and showed they are a class of endogenous lipid mediators that promote the resolution of various inflammatory conditions, including sepsis...