BioCentury
ARTICLE | Tools & Techniques

Bead-based kinase profiling

January 22, 2009 8:00 AM UTC

A team of researchers from the Broad Institute and other institutions has developed a high throughput screening method to profile activated tyrosine kinases in cancer cells.1 The group applied the approach to glioblastoma multiforme and showed that the technology could help identify new cancer targets missed by genomics approaches.

Although the team also published kinase activation profiles for an extensive number of cancer cell lines, corporate researchers said more proof of principle will be required to make effective use of the technology...