BioCentury
ARTICLE | Company News

Sigma-Aldrich, Autism Speaks deal

August 13, 2012 7:00 AM UTC

Sigma-Aldrich's Sigma Advanced Genetic Engineering (SAGE) Labs initiative and the advocacy group expanded a 2010 deal to develop rat models with modified autism-associated genes. Under the expansion, the partners will generate rat knockout models with the contactin associated protein-like 2 (CNTNAP2) and c-Met proto-oncogene (MET; HGFR) genes. Those rat models are expected to be available next year. Autism Speaks helped select the models and supported funding for initial characterization of the models. SAGE Labs is responsible for distribution and maintenance of the animals. ...