BioCentury
ARTICLE | Financial News

Stealth, AOBiome propose Hong Kong offerings

July 13, 2018 7:59 PM UTC

Stealth BioTherapeutics Corp. (Newton, Mass.) and AOBiome Therapeutics Inc. (Cambridge, Mass.) each proposed on July 3 to list on Hong Kong Exchanges and Clearing Ltd. (HKEX).

Stealth’s lead candidate is elamipretide, a mitochondrial-targeting tetrapeptide that binds and stabilizes cardiolipin to promote electron transfer and prevent apoptosis. The candidate is in a global Phase III trial to treat mitochondrial myopathy and a Phase II/III trial to treat Barth syndrome. Stealth plans to start a Phase IIb trial of the candidate to treat dry age-related macular degeneration (AMD) around year end and a Chinese Phase II/III trial to treat Leber’s hereditary optic neuropathy (LHON) in 1H19...

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AOBiome Therapeutics Inc.