BioCentury
ARTICLE | Emerging Company Profile

Nirmidas: Improving NIR-sightedness

Nirmidas' pGOLD amplifies fluorescent signals to boost assay sensitivity 100x

October 6, 2014 7:00 AM UTC

Nirmidas Biotech Inc.'s pGOLD platform can amplify the signal output of near-infrared fluorescent dyes over a hundredfold, which improves their sensitivity for low-concentration analytes in ELISA or other assays that rely on fluorescent readouts. The company will use the technology to develop in vitro diagnostics to diagnose diseases earlier and faster.

ELISA assays for disease diagnosis and monitoring have difficulty detecting low-concentration biomarkers. Radioimmunoassays are sensitive enough, but require handling radioactive materials and can take several days...