BioCentury
ARTICLE | Product Development

Basket cases

How Genentech and Novartis are using basket trials in cancer

June 13, 2016 7:00 AM UTC

Both the Genentech Inc. unit of Roche and Novartis AG are using basket trials to study targeted cancer agents more efficiently. Genentech's initial forays could yield rare subpopulation data to bring its marketed therapies into new indications, while Novartis is starting basket trials earlier in development to inform more traditional trials later on.

Both companies reported results at the American Society of Clinical Oncology meeting that show how the trials can yield actionable insights for companies...