ARTICLE | Product Development
Not dead yet
How to interpret CTAD data for Lilly, Biogen anti-amyloid mAbs in AD
December 17, 2016 3:37 AM UTC
The amyloid hypothesis may not be dead, but positive Phase Ib data for Biogen Inc.’s aducanumab notwithstanding, the preponderance of evidence still suggests that attacking plaques is unlikely to be an effective intervention for Alzheimer’s disease.
The near-simultaneous report that Eli Lilly and Co.’s solanezumab did not clear plaques in the failed EXPEDITION 3 trial and that aducanumab did - while also slowing cognitive decline - sent Biogen’s shares up and spawned headlines suggesting a breakthrough had been reached...
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