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BioCentury
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Explore BCIQ profiles by entering a target name.
BioCentury | Nov 5, 2024
Discovery & Translation

New frontiers in extracellular protein degradation

Six papers detail improved ways to degrade cell-surface cancer proteins through the lysosome
BioCentury | Mar 23, 2023
Emerging Company Profile

EpiBiologics tapping two lysosomal degradation mechanisms with $50M

The UCSF spinout is degrading membrane-bound and extracellular targets via bispecific antibody constructs it believes have a manufacturing advantage
BioCentury | Jan 6, 2023
Emerging Company Profile

BioCentury’s 2022 class of emerging companies

A snapshot of gene therapy and CAR T innovation, the emergence of protein stabilization, and new thinking in neurology
BioCentury | Sep 23, 2022
Discovery & Translation

PROTAC logic continues to evolve

New publications highlight bispecific antibody degraders as a way to eliminate a cell surface target
BioCentury | Jan 21, 2022
Emerging Company Profile

Avilar: Targeted degradation for extracellular proteins

RA Capital-incubated biotech is harnessing a receptor present on liver cells to internalize and degrade extracellular proteins
BioCentury | Nov 19, 2021
Finance

Nov. 18 Quick Takes: RA’s Avilar raises $60M seed for protein degradation tech

Sanofi invests in Owkin, plus Treadwell, Protego, BAKX, Fountain, Takeda-Denali
BioCentury | Aug 20, 2021
Product Development

The TAC universe grows beyond PROTACs

Inducing autophagy is becoming a popular strategy as targeting chimeras extend beyond protein degradation
BioCentury | Mar 27, 2021
Translation in Brief

Lentigen’s trispecific CAR Ts; plus a bispecific antiviral COVID-19 mAb, Wild Biotech, Kancera and more

BioCentury’s roundup of translational news
BioCentury | Aug 11, 2017
Strategy

The flip-side of immunotherapy

How immuno-oncology targets are spawning new therapies for inflammation
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