Soligenix preclinical data

Soligenix said RiVax in combination with ThermoVax vaccine thermostabilization technology retained its effectiveness and potency when stored at 40 degrees Celsius for >3 months whereas liquid RiVax was rapidly degraded and did not maintain its effectiveness when stored at the same temperature. The company said ThermoVax combines lyophilization technology, which removes water from pharmaceutical preparations, with aluminum adjuvants, secondary adjuvants and protein subunits to produce stable and potent vaccine formulations. RiVax, an aluminum-adjuvanted recombinant ricin A chain vaccine, is in Phase I testing and is being developed under FDA's Animal Rule, which allows marketing approval to be granted based on efficacy in relevant animal models and an acceptable safety risk profile in humans. ...