ARTICLE | Targets & Mechanisms
More mileage out of myelin
January 6, 2011 8:00 AM UTC
A team led by U.K. researchers has shown that retinoid X receptor
agonists can enhance remyelination of demyelinated axons in rodents by increasing the differentiation of oligodendrocyte precursor cells into oligodendrocytes.1 This remyelination activity could spark interest in repurposing the agonists, which are on the market and in the clinic for cancer...