ARTICLE | Targets & Mechanisms
S100A9-clot not, bleed not
May 29, 2014 7:00 AM UTC
Although the new generation of antithrombotic drugs provides marked improvements over warfarin, they all still carry bleeding risk. S100 calcium binding protein A9 could represent a new target that, when blocked, prevents thrombosis without increasing that risk.1
The new findings from U.S. researchers may hand a new indication to at least two companies-InflammatoRx Inc. and Active Biotech AB-developing inhibitors of this S100 protein to treat cancer, autoimmune diseases and inflammation...