ARTICLE | Translation in Brief
Guiding the way
Software tool predicts better CRISPR/Cas9 gene editing reagents
August 13, 2015 7:00 AM UTC
George Church's Harvard Medical School lab is addressing head-on one of the biggest limitations of CRISPR-based gene editing: Until the tech has been proven to cut only where and when needed, it won't make the jump from useful lab tool to human therapy.
In a study published last month in Nature Methods, the group presented a computational tool designed to increase the odds of generating reagents that are both safe and efficient...