BioCentury
ARTICLE | Product Development

Statins lead the way

October 11, 2004 7:00 AM UTC

The Heart of Inflammation

The involvement of inflammation in the etiology of coronary artery disease has led to the development of anti-inflammatory compounds to prevent or treat atherosclerosis and acute coronary syndrome. As yet, there is no conclusive evidence from a large, controlled trial showing the clinical benefit of a cardiovascular compound specifically designed as an anti-inflammatory. However, results from recent statin trials indicate that their anti-inflammatory activity plays a significant role in improving clinical outcomes, thus lending support to the hypothesis. ...