The broad Pacific

Pacific Biosciences Inc. filed to raise up to $200 million in an IPO, which could make it the largest biotech debut since the $215 million offering for gastrointestinal company Ironwood Pharmaceuticals Inc. (NASDAQ:IRWD) in February.

The company is already providing its PacBio RS system, a third-generation, single-molecule sequencing system based on its Single Molecule Real Time technology, to selected customers and anticipates a full commercial launch early next year...