ARTICLE | Distillery Therapeutics
Therapeutics: Homeodomain interacting protein kinase 2 (HIPK2); TAR DNA binding protein 43 (TDP-43; TARDBP)
June 16, 2016 7:00 AM UTC
In vitro and mouse studies suggest inhibiting HIPK2 could help treat ALS. In HEK cells and rat spinal motor neurons expressing a human ALS-associated TDP-43 mutation, an HIPK2 inhibitor tool compound ...