Neurology
Mouse studies suggest inhibiting RPS6KB1 could help treat SCI. In a mouse model of SCI, intracortical injection of a selective RPS6KB1 inhibitor tool compound increased regeneration of the cortico-spinal tract axons and sensorimotor function compared with vehicle. Next steps could include testing additional RPS6KB1 inhibitors in SCI models...
BCIQ Company Profiles
BCIQ Target Profiles
Ribosomal protein S6 kinase 70kDa polypeptide 1 (RPS6KB1) (S6K1)