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ARTICLE | Clinical News

Alnylam, Ionis fall after Pfizer's TTR cardiomyopathy readout

March 30, 2018 8:30 PM UTC

Pfizer Inc. (NYSE:PFE) said tafamidis meglumine met the primary endpoint in the Phase III ATTR-ACT trial to treat transthyretin (TTR) cardiomyopathy. Compared with placebo, the therapy reduced a combination of all-cause mortality and frequency of cardiovascular-related hospitalizations at 30 months.

Tafamidis is a small molecule that stabilizes the TTR protein and prevents its misfolding...

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