Portable device can produce GMP-quality proteins

A University of Maryland team developed a portable, customizable device that could enable the production of good manufacturing practice (GMP)-quality protein therapeutics at the point of care, which could be used in disaster-stricken or remote geographies.

Current GMP pipelines take weeks to manufacture biologics and cannot respond to rapid changes in demand. Previous studies have described methods to manufacture proteins on demand from freeze-dried cell extracts or devices that synthesize DNA and subsequently produce proteins. However, these methods did not produce the proteins under GMP conditions from start to finish...