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BioCentury
ARTICLE | Preclinical News

Salk team reports gene therapy can re-grow skin in cutaneous ulcers

Mark Zipkin
September 6, 2018 10:36 PM UTC

Researchers from Salk Institute for Biological Studies and colleagues developed a gene therapy delivering four transcription factors to regenerate epithelial cells from wound-resident mesenchymal cells in cutaneous ulcers.

By delivering reprogramming factors directly to a wound site, the therapy could help treat large cutaneous ulcers in which basal keratinocytes -- epidermal stem and progenitor cells -- are lost and wound healing is impaired...

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