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BioCentury
ARTICLE | Distillery Therapeutics

Infectious disease

Claire Quang
December 19, 2018 8:51 PM UTC

Non-human primate studies suggest soluble HIV env trimer given in combination with a saponin-based adjuvant could help prevent HIV infection. In macaques challenged with HIV, immunization with soluble HIV env trimer plus the saponin-based adjuvant decreased peak viremia and increased serum titers of neutralizing antibodies compared with no treatment and prevented infection for a median of 10 subsequent challenges. Next steps could include toxicity studies of the combination...

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BCIQ Company Profiles

Harvard Medical School

Scripps Research

University of Pennsylvania

BCIQ Target Profiles

HIV env