Neon data highlights epitope spread as key metric for neoantigen vaccines
Interim results from Neon's Phase Ib trial of NEO-PV-01 plus Opdivo nivolumab suggest proof of epitope spread will be a telling readout for neoantigen cancer vaccines. The data also point to tumor microenvironment-based predictors of therapeutic response.
Clinical data trickling in from early movers like Neon Therapeutics Inc. (NASDAQ:NTGN) could define biomarkers and set benchmarks for the crowded neoantigen vaccine field (see "Neo Wave")...
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