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ARTICLE | Targets & Mechanisms

Impaired wound healing: CD47’s latest safety hurdle?

New study adds wound healing problems to list of AEs CD47 companies need to monitor

Lauren Martz, Associate Editor
November 14, 2019 12:34 AM UTC

Just as anti-CD47 antibodies are getting past their first safety hurdle of hematological toxicities, a new study has cautioned that the antibodies could have a dangerous effect on wound healing.

In a paper published in Nature Communications on Nov. 1, a team led by University of Michigan professor Charles Parkos showed that anti-CD47 antibodies disrupt intestinal mucosal wound healing...

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BCIQ Company Profiles

Forty Seven Inc.

University of Michigan

BCIQ Target Profiles

CD47