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ARTICLE | Targets & Mechanisms

Colitis-associated somatic mutations yield new colorectal cancer target

Kyoto University suggests colitis-linked mutations may inhibit disease-associated colorectal cancer

January 11, 2020 12:22 AM UTC

Kyoto University team identifies colitis-associated somatic mutations that are lost in colitis-associated cancer to reveal a new colorectal cancer target.

A Japanese team has identified novel colorectal cancer targets by contrasting somatic mutations in cancerous vs. non-cancerous colon tissues in ulcerative colitis patients, rather than simply cataloging changes during tumorigenesis. ...

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