ARTICLE | Product Development
Master protocols emerge as a critical clinical tool against COVID-19
BioCentury is providing this story for free given the urgent need for information about the COVID-19 crisis. For more analysis, sign up for our daily email.
April 11, 2020 4:41 AM UTC
Updated on Apr 16, 2020 at 6:02 PM UTC
Master protocols are finally moving center stage, offering the fastest path to definitive answers on what will be the safest and most effective treatments for COVID-19. If master protocols prove their value in this disease, it may lower the activation energy for the trial designs to take hold in standard drug development after the crisis is over.
At least five master protocols are under way to test repurposed agents; the next step is to apply the structure to novel therapies...