Paracelsian preclinical data

PRLN (Ithaca, N.Y.) announced laboratory findings that show the combination of PN355 and AZT is effective at lower doses of AZT, which may reduce that drug's toxicity.

The inhibitor of tyrosine kinase, an enzyme that carries out signaling functions inside cells, appears to interfere with HIV's intracellular signals that contribute to the destruction of immune cells as well as the virus's replication. ...