ARTICLE | Product Development
ALS looks up as clinical pipeline explodes
Three late-stage readouts this year and multiple mechanisms in the clinic could lift the lid on ALS treatments
January 30, 2021 4:08 AM UTC
Propelled by new insights into disease biology, the clinical pipeline for ALS has grown to at least 43 programs attacking the disease from a dozen different directions. With six of those programs in Phase III testing, the largely empty arsenal for the fatal neurodegenerative disease could soon start to fill.
Undeterred by the long string of failures in Alzheimer’s disease, drug developers and investors are sustaining their rise in interest in neurodegenerative diseases, fueled in part by inroads made into disease pathology via human genetic studies...