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ARTICLE | Emerging Company Profile

Aulos: Tackling the IL-2 space with computational biology

Emerging Company Profile: Aulos believes its computationally designed mAb will stand out in IL-2

January 20, 2021 8:11 PM UTC

Apple Tree Partners launched Aulos into the crowded IL-2 space last week with a $40 million series A round and a computationally designed IL-2-binding antibody it thinks could have an edge in efficacy and safety.

Recombinant forms of IL-2 have been used for decades to treat melanoma, but toxicity is high due to the effects of the cytokine on blood vessels and the lungs...

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