ARTICLE | Product Development
Exosomes: a case study in manufacturing a new modality at scale
Exosome companies are anchoring their plans for progress in manufacturing innovation
May 28, 2021 9:34 PM UTC
A spate of exosome manufacturing innovations is industrializing the technology, enabling transition out of academia to the clinic, and biopharma BD teams have noticed.
Culturing and purifying exosomes at scale were the first translational hurdles faced by exosome companies looking to realize the promise of the membrane-bound vesicles to achieve targeted delivery of a range of therapeutic payloads without activating an immune response, an advantage over viral vectors and lipid nanoparticles. ...