DATA GRAPHICS | Data Byte
TRPM channel pipeline broadens beyond TRPM8
Biohaven the latest entrant with a license to KU Leuven’s small molecule TRPM3 antagonists
February 16, 2022 8:06 PM UTC
The TRPM pipeline will soon have its first Phase III candidate, and is beginning to broaden beyond TRMP8 to other channel family members.
Transient receptor potential (TRP) channels are calcium permeable, non-selective cation channels involved in a variety of functions throughout the body. The TRP family is subdivided into six subfamilies based on sequence similarity: TRPC (canonical), TRPM (melastatin), TRPV (vanilloid), TRPP (polycystin), TRPML (mucolipin) and TRPA (ankyrin)...