BioCentury
ARTICLE | Product Development

Synthetic lethality, protein degradation programs disappoint at AACR

C4, Zentalis and Repare are among the companies falling on AACR22 data

April 9, 2022 1:15 AM UTC


It was a rough day at the American Association for Cancer Research annual meeting for two of the most promising therapeutic classes: synthetic lethality and targeted degraders.

On Friday, shares of targeted degradation company C4 Therapeutics Inc. (NASDAQ:CCCC) fell $11.58 (51%) to $11.32 on new data from its IKZF1/IKZF3 degrader...

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