BioCentury
ARTICLE | Deals

Regeneron makes closing move on Checkmate, gaining cancer program in $250M deal

Regeneron adds partner Checkmate’s clinical TLR9 program via high-premium takeout, with stock near all-time low

April 19, 2022 2:43 PM UTC
Updated on Apr 19, 2022 at 9:00 PM UTC

Regeneron’s acquisition of Checkmate comes at a premium price of more than four times the biotech’s depressed market cap, though it’s roughly the amount the biotech raised during its seven-year history.

The deal gives Regeneron Pharmaceuticals Inc. (NASDAQ:REGN) a TLR9 agonist, vidutolimod, in clinical studies to treat melanoma, other skin cancers, and head and neck cancer. Among several combination trials is a Phase II study of vidutolimod plus Regeneron’s Libtayo cemiplimab-rwlc to treat anti-PD-1 refractory cutaneous squamous cell carcinoma and Merkel cell carcinoma...

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