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ARTICLE | Emerging Company Profile

Heqet: regenerating heart muscle cells via the Hippo pathway

King’s College spinout is inducing cardiomyocyte regeneration via nanoparticle-delivered miRNA

June 4, 2022 12:44 AM UTC

Turin-based Heqet is using miRNA compounds that transiently modulate the Hippo-YAP pathway to regenerate damaged heart tissue.

Heqet Therapeutics s.r.l. founder Mauro Giacca discovered Hippo pathway-modulating miRNAs while at the  International Centre for Genetic Engineering and Biotechnology (ICGEB) Trieste studying mechanisms of regeneration. ...

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