BioCentury
ARTICLE | Deals

GSK deal revives Spero’s clinical plan for oral antibiotic

Pharma pays $66M up front, allowing Spero to start a second Phase III trial following a complete response letter

September 22, 2022 10:11 PM UTC

After a months-long search for a partner, Spero has reached a deal with GSK that will enable the biotech to conduct a second Phase III trial of its oral carbipenem antibiotic for complicated urinary tract infections (cUTIs).

The deal gives Spero Therapeutics Inc. (NASDAQ:SPRO) a lifeline during a difficult year in which it had suspended its commercial activities, its cash reserves had dwindled and its stock had dipped below $1 intermittently...

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Spero Therapeutics Inc.

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DNA gyrase subunit B (GyrB)