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BioCentury
ARTICLE | Discovery & Translation

A mosaic nanoparticle vaccine for HCV; plus mitochondrial zinc finger base editors and more

BioCentury’s roundup of translational news

December 8, 2022 12:26 AM UTC

A team led by University of Amsterdam researchers, including Icosavax Inc. (NASDAQ:ICVX) co-founder Neil King, revealed in Nature Communications a mosaic nanoparticle vaccine co-displaying six different recombinant E2E1 glycoprotein immunogens that increased HCV neutralization compared with monovalent E2E1 nanoparticles in a rabbit model.

Icosavax has licensed patent applications regarding the nanoparticle system...

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