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ARTICLE | Emerging Company Profile

Gensaic: redosable, large-capacity gene therapies

MIT spinout harnessing the human phageome to develop gene delivery vehicles that solve the problems of AAVs

April 1, 2023 12:17 AM UTC

Gensaic is developing redosable gene-delivery vectors comprising particles derived from a bacteriophage that resides in the human gut. The company says the M13 bacteriophage can be engineered to target specific tissues and overcome the capacity, immunogenicity and manufacturing difficulties associated with AAVs.

Gensaic’s investors include Ovid Therapeutics Inc. (NASDAQ:OVID) and the Cystic Fibrosis Foundation, and it is operating out of Cambridge, Mass.-based incubator LabCentral. ...

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