Persistence, creative combinations behind Karuna’s $14B exit
BMS acquires Karuna, brightening the spotlight on schizophrenia, muscarinic receptors and neurology
Bristol Myers Squibb is making a major move into neuroscience through the $14 billion acquisition of Karuna Therapeutics — a deal that also solidifies neuropsychology’s position as a major interest area for big pharma, and proves that persistence in challenging but promising biology can pay off.
Bristol Myers Squibb Co. (NYSE:BMY) will acquire the biotech for $330 per share, a 53% premium over the biotech’s close on Thursday and a 35% premium over its 52-week-high. It’s the second large neurology acquisition this month following the proposed buyout of Cerevel Therapeutics Holdings Inc. (NASDAQ:CERE) and its next-generation schizophrenia asset by AbbVie Inc. (NASDAQ:ABBV) for $8.7 billion...
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Eukaryotic translation initiation factor 2B (EIF2B)
Fatty acid amide hydrolase (FAAH)
Monoglyceride lipase (MGLL) (MAGL)
Muscarinic acetylcholine receptor M1 (M1) (CHRM1) (HM1)
Transient receptor potential cation channel subfamily C member 4 (TRPC4)
Transient receptor potential cation channel subfamily C member 5 (TRPC5)