BioCentury
ARTICLE | Product Development

Tumor cell surface targets off the beaten path

Beyond the headlines at ASCO and AACR were a set of less traveled cancer targets, including neuronal proteins hijacked by solid tumors

June 18, 2024 11:03 PM UTC

Editor in Chief Simone Fishburn selected this story as one of BioCentury's Best of 2024. To see the full list, click here.

Hidden among the piles of ADCs and bispecifics against top targets such as HER2 are compounds targeting cancer cell surface proteins with less crowded pipelines. Presentations at this year’s ASCO and AACR provided a window into early-stage programs with less obvious targets, including a crop of neuronal regulators expressed by multiple solid tumors...