ARTICLE | Discovery & Translation
Science Spotlight: Reducing HIV load, new glycopeptide antibiotics, and more
BioCentury’s roundup of translational innovations
August 14, 2024 8:34 PM UTC
A group led by Leor Weinberger at University of California San Francisco developed a strategy to reduce HIV load in patients, and suggested the method may open an avenue to a “functional cure.”
The Science paper authors developed HIV therapeutic interfering particles (TIPs), engineered from portions of the HIV genome that contain deletions that suppress HIV replication. After administration, virions that incorporate the TIPS become non-pathogenic...